Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

High-sensitivity C-reactive protein: clinical importance.

Shari S Bassuk1, Nader Rifai, Paul M Ridker

  • 1Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

Current Problems in Cardiology
|July 20, 2004
PubMed
Summary

High-sensitivity C-reactive protein (hsCRP) is a key inflammation marker. Elevated hsCRP levels indicate higher cardiovascular risk, aiding in predicting heart attack and stroke in various patient groups.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Learning Lab: A new online learning tool in French for biologists and laboratory staff].

Annales de biologie clinique·2026
Same author

Sex steroid hormones, gonadotropins, and risk of testicular germ cell tumors: results from the STEED study.

Journal of the National Cancer Institute·2026
Same author

The Changing Face of Academic Laboratory Medicine-A Decade Later and Beyond.

Clinical chemistry·2025
Same author

High-sensitivity C-reactive protein, LDL cholesterol, lipoprotein(a) and 30-year risk of stroke in healthy women: a prospective, longitudinal cohort study.

The Lancet. Neurology·2025
Same author

Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women.

The New England journal of medicine·2024
Same author

High Lead Levels in 2 Independent and Authenticated Locks of Beethoven's Hair.

Clinical chemistry·2024

Area of Science:

  • Biomarkers and Cardiovascular Disease
  • Inflammation and Atherosclerosis
  • Clinical Risk Assessment

Background:

  • High-sensitivity C-reactive protein (hsCRP) is a sensitive marker of inflammation.
  • Inflammation plays a crucial role in the development of atherothrombotic diseases.
  • hsCRP has demonstrated prognostic value across diverse clinical scenarios.

Purpose of the Study:

  • To summarize epidemiologic data linking C-reactive protein (CRP) to atherothrombotic disease.
  • To provide clinical guidelines for using hsCRP in cardiovascular risk assessment.
  • To highlight the prognostic significance of hsCRP in both healthy individuals and those with established cardiovascular disease.

Main Methods:

  • Review of epidemiologic studies on CRP and cardiovascular events.

Related Experiment Videos

  • Analysis of hsCRP's predictive value across different risk strata.
  • Synthesis of data regarding hsCRP levels and associated cardiovascular risk.

    • Main Results:

    • hsCRP predicts incident myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death in healthy individuals.
    • hsCRP provides additional prognostic information beyond traditional risk factors like cholesterol, blood pressure, and metabolic syndrome.
    • hsCRP levels <1 mg/L, 1-3 mg/L, and >3 mg/L are associated with low, moderate, and high cardiovascular risk, respectively.

    Conclusions:

    • hsCRP is a valuable biomarker for assessing cardiovascular risk.
    • Clinical guidelines support hsCRP screening for enhanced cardiovascular risk stratification.
    • Understanding hsCRP levels aids in proactive cardiovascular disease management.