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Updated: Aug 23, 2026

Assessment and Characterization of Hyaloid Vessels in Mice
Published on: May 15, 2019
Ultrastructure of vitreomacular traction syndrome associated with persistent hyaloid artery
A Gandorfer1, M Rohleder, D Charteris
1Department of Ophthalmology, University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany. arnd.gandorfer@ak-i.med.uni-muenchen.de
Aim:
To demonstrate the ultrastructure of vitreomacular traction associated with persistent hyaloid artery.
Methods:
Pars plana vitrectomy was performed in a 66-year-old man with progressive vitreomacular traction associated with a persistent hyaloid artery. Epimacular tissue was peeled and processed for transmission electron microscopy.
Results:
Ultrastructural analysis revealed multiple sheets of cellular and collagenous components. Myofibroblasts and newly formed collagen were the predominant features. Fibrous astrocytes, fibroblasts, macrophages, and basement membrane were also present.
Conclusion:
The cellular composition of the epimacular tissue and high cellular activity suggest that persistence of the hyaloid artery may contribute to the development of vitreomacular traction.
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