Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary metastasectomy for pediatric solid tumors.

R M Abel1, J Brown, B Moreland

  • 1Department of Pediatric Surgery, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK.

Pediatric Surgery International
|July 20, 2004
PubMed
Summary

Pulmonary metastasectomy in children with isolated lung metastases from solid tumors is safe and effective. Aggressive surgical management, as part of combined therapy, leads to good long-term outcomes for most pediatric patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac MRI and acute myocarditis.

QJM : monthly journal of the Association of Physicians·2017
Same author

Prohormone convertase 2 (PC2) null mice have increased mu opioid receptor levels accompanied by altered morphine-induced antinociception, tolerance and dependence.

Neuroscience·2016
Same author

The effectiveness of a musical toothbrush for dental plaque removal: a comparative study.

Journal of the Indian Society of Pedodontics and Preventive Dentistry·2012
Same author

Warfarin therapeutic monitoring: is 70% time in the therapeutic range the best we can do?

Journal of clinical pharmacy and therapeutics·2011
Same author

Is the routine placement of a CSF reservoir following endoscopic third ventriculostomy justified?

British journal of neurosurgery·2009
Same author

Endobronchial obstruction from an intubation stylet sheath.

Neonatology·2008

Area of Science:

  • Pediatric Oncology
  • Thoracic Surgery
  • Surgical Oncology

Background:

  • Pediatric thoracic malignancy often presents as pulmonary disease secondary to childhood solid tumors.
  • Management of isolated pulmonary metastases in adults is established, but long-term outcomes in children are less documented.

Purpose of the Study:

  • To assess the long-term outcomes of pulmonary metastasectomy in pediatric patients with isolated pulmonary metastases.
  • To evaluate the safety and efficacy of surgical intervention for lung metastases in children.

Main Methods:

  • Retrospective study of 20 children undergoing surgery for isolated pulmonary metastases over 12 years.
  • Analysis of patient demographics, tumor types (Wilms' tumor, osteogenic sarcoma, rhabdomyosarcoma, hepatoblastoma, teratoma), surgical procedures, and follow-up data.

Related Experiment Videos

  • Inclusion of preoperative imaging (contrast-enhanced CT of head and chest, chest X-ray) in assessment.

    • Main Results:

    • 16 out of 20 children remain alive and well with a mean follow-up of 8 years.
    • 19 children were discharged within 10 days of surgery, indicating good tolerance.
    • One early complication (pneumonia) and four late deaths due to cranial metastases were reported.

    Conclusions:

    • Results support an aggressive surgical approach for isolated pulmonary metastases in children as part of combined therapy.
    • Bilateral synchronous and metachronous thoracotomy is well tolerated in the pediatric population.
    • Comprehensive preoperative assessment, including advanced imaging, is crucial for surgical planning.