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Related Experiment Videos

Electrogastrography differentiates reflux disease with or without dyspeptic symptoms.

Chien-Lin Chen1, Hsien-Hong Lin, Lu-Chin Huang

  • 1Department of Medicine, Buddhist Tzu Chi General Hospital and University School of Medicine, Hualien 970, Taiwan. clchen@tzuchi.org.tw

Digestive Diseases and Sciences
|July 21, 2004
PubMed
Summary

Patients with gastroesophageal reflux disease (GERD) and dyspepsia show distinct gastric electrical activity patterns. These findings suggest differences in stomach function between GERD patients with and without dyspeptic symptoms.

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Area of Science:

  • Gastroenterology
  • Physiology

Background:

  • Gastroesophageal reflux disease (GERD) often co-occurs with dyspepsia.
  • Gastric myoelectrical activity may differentiate GERD patient subgroups.

Purpose of the Study:

  • To investigate if gastric myoelectrical characteristics can distinguish GERD patients with dyspeptic symptoms (GERD+) from those without.
  • To analyze electrogastrograms (EGGs) in GERD patients with and without dyspepsia.

Main Methods:

  • Recruited 20 GERD+ patients and 17 GERD patients.
  • Assessed gastric myoelectrical activity using electrogastrograms (EGGs).
  • Compared water ingestion volumes and EGG power distribution in different frequency ranges.

Main Results:

  • GERD+ patients ingested smaller water volumes (P < 0.05).

Related Experiment Videos

  • GERD+ patients had significantly less normal 3-cpm gastric electrical activity (P = 0.01).
  • GERD+ patients exhibited increased power in bradygastria (P = 0.005) and tachygastria ranges post-ingestion (P < 0.01).

    • Conclusions:

    • GERD+ patients demonstrate more gastric dysrhythmias compared to GERD patients.
    • Altered gastric myoelectrical activity correlates with altered stomach fullness perception in GERD+ patients.