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[Brain aging and calcium antagonist drugs. A preliminary open study with nimodipine]
V Centonze1, C Massaro, B M Polito
1Istituto di Clinica Medica I, Università degli Studi di Bari.
La Clinica Terapeutica
|January 1, 1992
Abstract:
Forty patients aged 65-80 with minor-medium signs of brain aging were treated for 6 months with daily 90 mg doses of nimodipine. Treatment was well tolerated in that the minor side effects reported by a few of the patients never required withdrawal of the drug. Treatment proved useful, as shown by a variety of mental tests, in 69.5% of cases. In 20% conditions remained unchanged and in 9.5% further deterioration was observed. The authors conclude that nimodipine may be considered a useful therapeutic resource for phenomena of brain aging.