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Anxiety disorders and schizophrenia.

Jacqueline E Muller1, Liezl Koen, Seedat Soraya

  • 1Medical Research Council Unit on Anxiety Disorders, Department of Psychiatry, University of Stellenbosch, PO Box 19063, Tygerberg, Cape Town 7505, South Africa. jemuller@sun.ac.za

Current Psychiatry Reports
|July 21, 2004
PubMed
Summary

Anxiety symptoms are common in schizophrenia, potentially a core feature. Assessing and treating these comorbid anxiety disorders is crucial for patient care.

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Area of Science:

  • Psychiatry
  • Neuroscience

Background:

  • Anxiety symptoms and disorders are frequently observed in individuals diagnosed with schizophrenia.
  • The relationship between schizophrenia and anxiety requires further investigation into its epidemiological, phenomenological, and neurobiological aspects.

Purpose of the Study:

  • To review the current literature on the epidemiology, phenomenology, and neurobiological underpinnings of anxiety symptoms and disorders comorbid with schizophrenia.
  • To highlight the clinical implications of these comorbidities.

Main Methods:

  • A comprehensive literature search was conducted using Medline.
  • Keywords included "schizophrenia" and "anxiety symptoms" or "anxiety disorders".

Main Results:

  • Evidence suggests anxiety may be a core symptom dimension in schizophrenia, though more research is needed.

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  • Comorbid obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder occur more frequently than by chance in schizophrenia.
  • The underlying mechanisms and clinical implications of these associations require further study.

    • Conclusions:

    • Anxiety symptoms and disorders are significantly associated with schizophrenia.
    • There is a need for routine assessment and treatment of comorbid anxiety in schizophrenia patients.
    • Further research is essential to elucidate the mechanisms and optimize management strategies.