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Cardiovascular magnetic resonance and the role of adenosine pharmacologic stress

Dudley J Pennell1

  • 1Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom. d.pennell@imperial.ac.uk

The American Journal of Cardiology
|July 21, 2004
PubMed

Insights

Cardiovascular magnetic resonance (CMR) provides high-resolution heart imaging for various conditions. Its accuracy makes it ideal for serial measurements and emerging applications like myocardial perfusion assessment.

Area of Science:

  • Cardiovascular Imaging
  • Medical Diagnostics
  • Cardiac MRI

Background:

  • Cardiovascular magnetic resonance (CMR) is an advanced imaging technique.
  • It offers high spatial resolution for cardiac and vascular assessment.
  • CMR is clinically established for conditions like congenital heart disease, tumors, and cardiac function.

Purpose of the Study:

  • To highlight the established clinical applications of CMR.
  • To discuss emerging clinical applications of CMR, including myocardial perfusion and viability.
  • To explain the methodology of perfusion CMR studies.

Main Methods:

  • Utilizes high spatial resolution imaging of the heart.
  • Employs pharmacologic stress (e.g., adenosine) in perfusion studies.
  • Assesses myocardial perfusion by evaluating contrast agent delivery differences.

Main Results:

  • CMR demonstrates high interstudy reproducibility for left ventricular volumes, ejection fraction, and mass.
  • It is an ideal noninvasive technique for serial cardiac measurements.
  • Emerging applications like myocardial perfusion, infarction, and viability evaluation are nearing routine clinical use.

Conclusions:

  • CMR is a versatile and accurate imaging modality for cardiac assessment.
  • Its reliability supports serial monitoring of cardiac conditions.
  • CMR is expanding into advanced applications for diagnosing myocardial issues.

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