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Related Experiment Videos

Nail psoriasis.

E M Farber1, L Nall

  • 1Psoriasis Research Institute, Palo Alto, California 94301.

Cutis
|September 1, 1992
PubMed
Summary
This summary is machine-generated.

Nail psoriasis affects up to 50% of individuals and presents with characteristic nail changes. This study offers management strategies for preventing and controlling nail psoriasis, which is often resistant to treatment.

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Area of Science:

  • Dermatology
  • Rheumatology

Background:

  • Psoriatic nail involvement is a frequent manifestation of psoriasis, impacting patients across all age groups.
  • Nail changes include pitting, discoloration, onycholysis, subungual hyperkeratosis, crumbling, grooving, and splinter hemorrhages.

Purpose of the Study:

  • To review and suggest effective measures for the prevention and control of psoriatic nail disease.
  • To address the challenges in treating nail psoriasis due to its slow response to therapy.

Main Methods:

  • Review of current therapeutic approaches for nail psoriasis.
  • Identification of suggested management strategies for patient benefit.

Main Results:

  • Psoriatic nail involvement is common, with diverse clinical presentations.

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  • Current treatments like corticosteroids, 5-fluorouracil, photochemotherapy, oral retinoids, methotrexate, and nail avulsion show limited consistent efficacy.
  • Nails are notoriously difficult to treat and respond slowly to interventions.

    • Conclusions:

    • Effective management of nail psoriasis remains a challenge.
    • Suggested preventive and control measures may offer benefits to patients.
    • Further research into novel and more effective treatments is warranted.