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Effect of sildenafil citrate on retinal functions: preliminary report on Humphrey visual field analysis
Hakan F Oner1, Güven Aslan, Erkan Kurtulan
1Department of Ophthalmology, Dokuz Eylül University School of Medicine, Izmir, Turkey.
Objective:
To assess the effect of sildenafil citrate treatment on visual field analysis (VFA) in patients using sildenafil citrate for erectile dysfunction.
Materials And Methods:
In this prospective study on 18 male volunteers with erectile dysfunction, bilateral VFA was performed using the Humphrey 30-2 central standard threshold test. White-on-white (W/W) and blue-on-yellow (B/Y) protocols were used prior to treatment (baseline VFA) and after treatment (repeat VFA) with sildenafil citrate. W/W and B/Y baseline VFA and repeat VFA mean deviations (MD) were compared.
Results:
The baseline MD for W/W and B/Y protocols were -1.34 +/- 1.8 and -2.59 +/- 2.1 dB, respectively, whereas the mean repeat MD for W/W and B/Y protocols were -1.79 +/- 2.21 and -2.83 +/- 3.31 dB, respectively. There was no statistically significant difference between W/W and B/Y baseline and repeat VFA with respect to MD (p > 0.05).
Conclusion:
Sildenafil citrate causes no significant changes in Humphrey VFA in patients with erectile dysfunction.