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Technology evaluation: rh lactoferrin, Agennix.

Jeanette H Andersen1

  • 1University Hospital of North Norway, Department of Medical Microbiology, Tromso N-9038, Norway. jeanettea@nfh.uit.no

Current Opinion in Molecular Therapeutics
|July 22, 2004
PubMed
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Agennix is developing recombinant human lactoferrin for treating cancer, asthma, and wounds. This glycoprotein exhibits antibiotic, anti-inflammatory, and immunomodulatory properties and is in Phase II clinical trials.

Area of Science:

  • Biochemistry
  • Immunology
  • Pharmacology

Background:

  • Lactoferrin is a glycoprotein with known antibiotic, anti-inflammatory, and immunomodulatory activities.
  • Recombinant human lactoferrin (rhLactoferrin) is being developed as a therapeutic agent.

Purpose of the Study:

  • To evaluate the potential of rhLactoferrin in treating various medical conditions.
  • To investigate rhLactoferrin for applications in oncology, pulmonology, and wound healing.

Main Methods:

  • Development of recombinant human lactoferrin.
  • Ongoing Phase II clinical trials to assess efficacy and safety.

Main Results:

  • The abstract does not contain specific results from clinical trials.

Related Experiment Videos

  • The development of rhLactoferrin is progressing through clinical evaluation.
  • Conclusions:

    • rhLactoferrin shows promise as a therapeutic agent due to its multifaceted biological activities.
    • Further clinical investigation is warranted to establish its therapeutic value in cancer, asthma, and chronic wounds.