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Updated: Aug 23, 2026
Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT
Published on: May 2, 2017
A method to quantify the uptake rate of 2-[18F]fluoro-2-deoxy-D-glucose in tissues
Eric Laffon1, Michèle Allard, Roger Marthan
1Service de Médecine Nucléaire, Hôpital du Haut_Lévêque, Centre Hospitalo_Universitaire de Bordeaux, Bordeaux, France. elaffon@u_bordeaux2.fr
Abstract:
A two-compartment model is used to derive the tissue time-activity curve of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG). At the later phase of the 18F-FDG activity in the tissue, the model leads to a method which allows the assessment of the 18F-FDG uptake rate constant. The proposed method is both compared with the standard uptake value (SUV) method and with Patlak's graphical analysis.
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