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Isolation and Expansion of Cytotoxic Cytokine-induced Killer T Cells for Cancer Treatment
Published on: January 24, 2020
Targeting cytotoxic T lymphocytes for cancer immunotherapy
1Cancer Research UK Breast Cancer Biology Group, Division of Cancer Studies, Guy's King's and St Thomas's School of Medicine, Guy's Hospital, St Thomas Street, London SE1 9RT, UK.
Abstract:
In light of their preeminent role in cellular immunity, there is considerable interest in targeting of cytotoxic T-lymphocytes to cancer. This review summarises the active and passive immunotherapeutic approaches under development to achieve this goal, emphasising how recent advances in tumour immunology and gene transfer have impacted upon this field.
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