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Updated: Aug 13, 2026

08:49
Exosomal miRNA Analysis in Non-small Cell Lung Cancer (NSCLC) Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool
Published on: May 27, 2016
Nuclear survivin as a biomarker for non-small-cell lung cancer
B Lu1, A Gonzalez, P P Massion
1Department of Radiation Oncology, Vanderbilt Ingram, Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. bolu@vanderbilt.edu
British Journal of Cancer
|July 22, 2004
Abstract:
Survivin inhibits apoptosis and promotes mitosis. We determined whether nuclear or cytoplasmic localisation of survivin predicts survival of 48 patients with resected non-small-cell lung cancer (NSCLC). Patients with nuclear staining of survivin had significantly worse survival (relative risk: 3.9, P=0.02). Therefore, survivin may be a biomarker for NSCLC.

