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07:49
Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model
Published on: April 13, 2015
The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
P A McArdle1, K Canna, D C McMillan
1University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, UK.
British Journal of Cancer
|July 22, 2004
Abstract:
The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer (n=80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27-4.83, P=0.008) and CD4+ T-lymphocyte count (HR 2.29, 95% CI 1.25-4.22, P=0.008) had independent significance. Increased CD4+ T-lymphocyte infiltration within the tumour was stage independent and associated with poor outcome in patients with prostate cancer.