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Psychological interventions for non-ulcer dyspepsia
The Cochrane Database of Systematic Reviews
|July 22, 2004
Summary
Psychological interventions may benefit non-ulcer dyspepsia (NUD) symptoms long-term, but current evidence is insufficient to confirm efficacy. Further research is needed to establish the effectiveness of these therapies for NUD patients.
Area of Science:
- Gastroenterology
- Psychiatry
- Evidence-based Medicine
Background:
- Non-ulcer dyspepsia (NUD) is associated with psychological distress, including anxiety and depression.
- The effectiveness of psychological interventions for NUD remains uncertain.
Purpose of the Study:
- To review the effectiveness of various psychological interventions for NUD.
- To assess improvements in dyspepsia symptom scores and quality of life.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) and quasi-randomized studies.
- Searched multiple databases including Cochrane, MEDLINE, EMBASE, CINAHL, and PsycLIT.
- Included studies on psychotherapy, psychodrama, CBT, relaxation therapy, and hypnosis for NUD.
Main Results:
- Identified four trials with diverse psychological interventions; meta-analysis was not possible.
- All trials indicated potential benefits for dyspepsia symptoms lasting one year.
- Concerns regarding small sample sizes, statistical adjustments, low recruitment, and high dropout rates were noted.
Conclusions:
- Insufficient evidence currently confirms the efficacy of psychological interventions for NUD.
- Long-term benefits are plausible, suggesting potential use for severe, refractory NUD.
- No evidence exists on combined pharmacological and psychological therapy for NUD.