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Nasal versus oral route for placing feeding tubes in preterm or low birth weight infants
1Pediatrics, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8. judith.hawes@sickkids.ca
Insights
Limited evidence exists on feeding tube placement in preterm infants. More research is needed to determine if nasal or oral feeding tubes are safer and more effective for infant growth and development.
Area of Science:
- Neonatal care
- Pediatric gastroenterology
- Clinical nutrition
Background:
- Enteral feeding tubes are crucial for preterm and low birth weight infants.
- Tube placement can be nasal or oral, each with potential complications.
- Nasal tubes may affect respiration, while oral tubes risk displacement and vagal stimulation.
Purpose of the Study:
- To evaluate randomized controlled trials comparing nasal versus oral feeding tubes in preterm infants.
- To assess effects on infant growth, development, and adverse events.
Main Methods:
- Searched Cochrane Neonatal Group, MEDLINE, EMBASE, CINAHL, and other databases.
- Included randomized and quasi-randomized controlled trials.
- Extracted data on relative risk and mean differences.
Main Results:
- Only one eligible trial with 42 infants was identified.
- The trial focused on apnea and periodic breathing, not growth and development.
- Data on primary outcomes for this review were not reported.
Conclusions:
- Insufficient data exist to guide clinical practice regarding feeding tube placement.
- A large randomized controlled trial is necessary to compare nasal and oral feeding tubes.
- Further research should assess effects on growth, development, and adverse consequences.
Background:
Enteral feeding tubes for preterm or low birth weight infants may be placed via either the nose or mouth. Nasal placement may compromise respiration. However, orally placed tubes may be more prone to displacement, local irritation, and vagal stimulation.
Objectives:
To assess the available evidence from randomised controlled trials concerning the effects of nasally placed compared with orally placed feeding tubes on growth and development, and the incidence of adverse consequences in preterm or low birth weight infants.
Search Strategy:
We used the standard search strategy of the Cochrane Neonatal Review Group, including electronic searches of the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 2, 2004), MEDLINE (1966 - April 2004), EMBASE (1988 - April 2004), and CINAHL (1982- April 2004), conference proceedings, and previous reviews.
Selection Criteria:
Randomised or quasi-randomised controlled trials that compared the use of the nasal versus oral route for placing feeding tubes in preterm or low birth weight infants.
Data Collection And Analysis:
We extracted data using the standard methods of the Cochrane Neonatal Review Group, with separate evaluation of trial quality and data extraction by each author, and analysis of data using relative risk, risk difference and mean difference.
Main Results:
We found only one eligible trial. Forty-two infants participated in the study. This primary aim of the trial was to assess the effect of oral versus nasal placement of feeding tubes on the incidence of apnea and periodic breathing in preterm infants. The trial did not report data on the pre-specified primary outcomes for this review (growth and development).
Reviewers' Conclusions:
There are insufficient data available to inform practice. A large randomised controlled trial is required to determine if the use of nasally placed feeding tubes compared with orally placed feeding tubes improves growth and development, without increasing adverse consequences in preterm or low birth weight infants.
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