Related Experiment Video
Updated: Aug 23, 2026

Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
Myasthenia gravis and premature ovarian failure
Monique M Ryan1, H Royden Jones
1Department of Neurology, Lahey Clinic, 41 Mall Road, Burlington, Massachusetts 01805, USA.
Abstract:
We describe a patient who developed seropositive myasthenia gravis 16 years after she was diagnosed with autoimmune premature ovarian failure with antibodies to the receptor for follicle-stimulating hormone (FSH). Although thymectomy led to improvement of her myasthenic symptoms, menses did not resume. Such combined seropositivity for antibodies to acetylcholine and ovarian hormone receptors in a patient with myasthenia gravis and premature ovarian failure may reflect common disease mechanisms, although the precise pathogenesis of these disorders remains ill-defined.
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