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Updated: Aug 23, 2026

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
Published on: May 20, 2020
[Clinical analysis of lymphangioleiomyomatosis]
Peng Gao1, Rong Huang, Bai-qiang Cai
1Department of Respiratory Disease, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Objective:
To improve the diagnosis and treatment of lymphangioleiomyomatosis (LAM).
Methods:
The clinical data of four cases of lymphangioleiomyomatosis diagnosed in our hospital were analyzed and corresponding literature was reviewed.
Results:
Lymphangioleiomyomatosis, a rare disorder of unknown cause that occured almost exclusively in women of child bearing ages, was characterized microscopically by atypical smooth muscle proliferation. It could occur as a sporadic diseases or as a part of tuberous sclerosis complex (TSC). LAM was associated with progressive dyspnea, recurrent spontaneous pneumothoraces, chylous effusions, and hamartomas.
Conclusion:
Clinicians should be familiar with the characteristics of LAM so that diagnosis and treatment can be made earlier to improve the prognosis.
