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Updated: Aug 14, 2026

The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury
Published on: October 21, 2017
Protective effect of Lawsonia alba Lam., against CCl4 induced hepatic damage in albino rats
Manoj Bhandarkar1, Aqueel Khan
1Department of Biochemistry, Nagpur University, L.I.T. Premises, Amravati Road, Nagpur 440010, India. manoj_3902@rediffmail.com
Abstract:
The oral administration in varying doses of aqueous suspension of extract of L. alba, bark extract to rats for 10 days afforded good hepatoprotection against CCl4 induced elevation in serum marker enzymes, serum bilirubin, liver lipid peroxidation and reduction in total serum protein, liver glutathione, glutathione peroxidase, glutathione-s-transferase, glycogen, superoxide dismutase and catalase activity. The results suggest hepatoprotective and antioxidant activity of extract of L. alba bark.

