Related Experiment Video
Updated: Aug 3, 2026

Murine Renal Transplantation Procedure
Published on: July 9, 2009
[Sildenafil citrate for erectile dysfunction in male kidney transplant recipients]
Feng Liu1, Genfu Zhang, Xining Ji
1Renal Disease Research Center, Department of Urinary Surgery, XinQiao Hospital, Third Military Medical University, Chongqing 400037, China. liufwh@hotmail.com
Objective:
To evaluate the efficacy and safety of sildenafil citrate in man kidney transplant recipients with erectile dysfunction.
Methods:
One hundred and seventy married males, aged 26 approximately 50 years, who had received kidney transplantations at least half a year before and whose serum creatinine was under 133 umol/l, were selected randomly in the study. Their sexual function was investigated according to the International Index of Erectile Function-5 (IIEF-5), and those with erectile dysfunction (ED) were treated with oral sildenafil citrate for 6 months. The efficacy was assessed by IIEF-5.
Results:
Fifty-three men with ED received oral sildenafil citrate for 6 months. At the end of the treatment, each index in IIEF-5 increased significantly. There were no interactions between sildenafil and cyclosporine and there was no significant adverse effect of sildenafil on the graft function.
Conclusion:
Sildenafil is an effective and safe agent for the treatment of ED in kidney transplant recipients.
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