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[Serum selenium level as a diagnostic parameter in breast cancer]
1Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Helvetica Chirurgica Acta
|May 1, 1992
Summary
Low blood serum selenium levels may indicate breast cancer. This study found significantly lower selenium in breast cancer patients compared to healthy women, suggesting its potential as a noninvasive diagnostic marker.
Area of Science:
- Biochemistry
- Oncology
- Clinical Diagnostics
Context:
- Investigated selenium levels in blood serum.
- Included breast cancer patients, mastopathy patients, and healthy controls.
- Data collected from subjects in the Zagreb area.
Purpose:
- To determine if serum selenium levels differ between breast cancer patients, mastopathy patients, and healthy individuals.
- To explore the potential of serum selenium as a noninvasive diagnostic marker for breast cancer.
Summary:
- Serum selenium levels were significantly lower in breast cancer patients (41-58 µg/L) compared to healthy subjects (73-89 µg/L) (p < 0.001).
- Subjects with mastopathy (67-70 µg/L) showed no significant difference from healthy women but were significantly different from breast cancer patients (p < 0.001).
Impact:
- Serum selenium determination shows promise as a noninvasive diagnostic tool for malignant breast disease.
- Findings suggest a potential role for selenium in breast cancer assessment and possibly prevention.
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