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Cloning, characterization and expression of the polypeptide release factor gene, eRF1, of Blepharisma japonicum

Wei Wang1, Bao-Feng Chai, Klaus Heckmann

  • 1Institute of Biotechnology, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, P.R. China.

Biotechnology Letters
|July 23, 2004
PubMed

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Exon Recombination02:32

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
Exon shuffling follows “splice frame rules.” Each exon has three reading...