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Updated: Aug 23, 2026

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
Published on: September 10, 2014
Compact, high voltage power supply for the lab-on-a-chip
Greg E Collins1, Peter Wu, Qin Lu
1Chemistry Division, Code 6112, Naval Research Laboratory, 4555 Overlook Ave. S.W., Washington, DC 20375, USA.
Abstract:
The design, construction and operation of a simple, inexpensive and compact high voltage power supply (HVPS) for use in conjunction with a simple cross capillary electrophoresis microchip is presented. The microchip HVPS utilizes a single high voltage power supply (15 kV), a voltage-divider network, to give the voltages necessary to operate a gated injection valve, and two high voltage relays for switching between the open and closed gate sequences of the injection. In order to accommodate the application of different simple cross microchip dimensions, a set of equations for defining the resistor network and ensuring proper gate performance are presented.
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