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[Leydig cell tumor presenting as precocious pseudopuberty in a 4-year-old boy]
Francisco Javier Alonso Domínguez1, Vicente Angel Osorio Acosta
1Hospital Comandante Manuel Fajardo, Ciudad de la Habana, Cuba. falonso@manfa.sld.cu
Objectives:
To report one case of isosexual precocious pseudopuberty in a 4-year-old boy caused by an interstitial cell testicular tumor.
Methods:
Physical exam, blood tests, hormonal determinations, adrenal suppression tests, bone age, orchiectomy and pathologic study of the specimen were performed.
Results:
Physical examination showed a boy with muscle development, acne; body, sexual and face hair corresponding to an older boy; with increased volume of the left testicle and infantile contralateral testicle. Urinary 17-ketosteroids were elevated and did not decrease after dexametasone. Bone age corresponded to an 11-year-old standard. Pathologic study showed an interstitial cell tumor. Puberty changes disappeared after orchiectomy.
Conclusions:
This diagnosis should be taken into consideration in every case of accelerated sexual development in a boy with testicular tumor and without maturation of the contralateral testicle.