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Updated: Aug 23, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
Published on: July 26, 2017
The potential for Toll-like receptors to collaborate with other innate immune receptors
Subhankar Mukhopadhyay1, Jurgen Herre, Gordon D Brown
1Sir William Dunn School of Pathology, South Parks Road, Oxford OX1 3RE, UK.
Abstract:
Cells of the innate immune system express a large repertoire of germ-line encoded cell-surface glycoprotein receptors including Toll-like receptors (TLRs). TLRs recognize conserved motifs on microbes and induce inflammatory signals. Evidence suggests that individual members of the TLR family or other non-TLR surface antigens either physically or functionally interact with each other and cumulative effects of these interactions instruct the nature and outcome of the immune response to a particular pathogen.
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