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Related Experiment Videos

Corneal epithelial disease.

Tim J Cutler1

  • 1Animal Eye Specialty Clinics of South Florida, 3421 Forest Hill Boulevard, West Palm Beach, FL 33406, USA. cutlert@earthlink.net

The Veterinary Clinics of North America. Equine Practice
|July 24, 2004
PubMed
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This review covers corneal epitheliopathies, including indolent ulcers and neoplasia, distinct from stromal diseases. Newer diagnostic and therapeutic strategies for these challenging corneal conditions are discussed.

Area of Science:

  • Ophthalmology
  • Veterinary Ophthalmology

Background:

  • Corneal diseases encompass a range of conditions affecting the cornea.
  • Epithelial diseases, or epitheliopathies, are distinct from stromal diseases and require specific diagnostic and treatment approaches.
  • While corneal ulcers are common, other epithelial conditions like indolent ulcerations, neoplasia, and eosinophilic keratitis present unique challenges.

Purpose of the Study:

  • To review conditions primarily affecting the corneal epithelium.
  • To differentiate these from corneal stromal diseases.
  • To discuss newer therapies and surgical strategies for challenging epithelial corneal lesions.

Main Methods:

  • Literature review of corneal epitheliopathies.
  • Discussion of diagnostic challenges.

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  • Overview of current and emerging treatment modalities.

    • Main Results:

    • Corneal epitheliopathies include subtle epithelial diseases, uninfected indolent superficial ulcerations, corneal neoplasia, and eosinophilic keratitis.
    • Fungal plaques represent an unusual chronic epithelial infection.
    • These conditions, though less common than ulcers, pose significant diagnostic and therapeutic hurdles.

    Conclusions:

    • Accurate diagnosis of corneal epitheliopathies is crucial for effective treatment.
    • Novel therapeutic and surgical approaches offer improved outcomes for challenging cases.
    • Further research into the pathogenesis and management of these conditions is warranted.