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Updated: Aug 23, 2026

Near-Infrared Spectroscopy During Reactive Hyperemia for the Assessment of Lower Limb Vascular Function
Published on: March 22, 2024
Post-occlusive reactive hyperemia in patients with peripheral vascular disease
Xuefeng Cheng1, Jian-Min Mao, Xiaorong Xu
1ViOptix Inc., 44061-B Old Warm Spring Blvd., Fremont, CA 94538, USA.
Abstract:
We measured tissue oxygen saturation (StO2) changes during a post-occlusive reactive hyperemia (PORH) test on lower extremities of peripheral vascular disease (PVD) patients and healthy controls. The StO2 changes were measured by the near-infrared tissue oximeter prototyped by ViOptix Inc. We found that PVD indicators may include the post-occlusive StO2 reperfusion rate, the time duration of the reperfusion phase in a PORH test, and the StO2 dispersion rate in reactive hyperemia. We suggest critical values of these indicators for PVD assessments.
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