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Updated: Aug 23, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
Flail arm syndrome: a clinical variant of amyotrophic lateral sclerosis
A Czaplinski1, A J Steck, P M Andersen
1Department of Neurology, University of Basel, Basel, Switzerland. aczaplinski@uhbs.ch
Abstract:
We describe a case of a 65-year old patient diagnosed with amyotrophic lateral sclerosis. The clinical findings, with symmetric, predominantly proximal wasting and weakness of both arms (especially of the infra-, supraspinatus and deltoideus) leading to severe functional disability and contrasting with preserved independent ambulation and sparing of bulbar muscles, were consistent with the proposed criteria of the so-called flail arm syndrome. Based on our case we characterize the clinical features of flail arm syndrome and review the literature.
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