Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Predicting factors for depression in multiple sclerosis].

R Alarcia1, J R Ara, J Martín

  • 1Unidad de Enfermedades Desmielinizantes, Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza. lcarmen@comz.org

Neurologia (Barcelona, Spain)
|July 27, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two related genes encoding extremely hydrophobic proteins suppress a lethal mutation in the yeast mitochondrial processing enhancing protein.

The Journal of biological chemistry·1992
Same author

Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity.

The EMBO journal·1992
Same author

Effect on sensitisation of giving HLA-DR-matched blood to potential renal transplant recipients.

Transplantation proceedings·1992
Same author

Autolymphocyte therapy for metastatic renal cell carcinoma: initial clinical results from 335 patients treated in a multisite clinical practice.

Transplantation proceedings·1992
Same author

Prevention of protein denaturation under heat stress by the chaperonin Hsp60.

Science (New York, N.Y.)·1992
Same author

Routine quantitative analysis of brain and cerebrospinal fluid spaces with MR imaging.

Journal of magnetic resonance imaging : JMRI·1992

Depression affects nearly half of multiple sclerosis (MS) patients and is linked to chronic fatigue and poorer social status, not disability or interferon treatment.

Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Research

Context:

  • Multiple sclerosis (MS) is a chronic demyelinating disease affecting the central nervous system.
  • Depression is a common comorbidity in MS, impacting patient quality of life.
  • Understanding depression's prevalence and correlates in MS is crucial for effective management.

Purpose:

  • To determine the frequency and intensity of depression in multiple sclerosis (MS) patients.
  • To assess the detection rate of depression in MS patients.
  • To investigate the relationship between depression and beta interferon treatment, clinical factors, and paraclinical variables.

Summary:

  • This study analyzed 100 MS patients, finding depression in 44%.
  • Depression was not associated with neurological disability, disease duration, clinical form, interferon treatment, or sleep disorders.

Related Experiment Videos

  • However, depression correlated significantly with chronic fatigue and Expanded Disability Status Scale (EDSS) scores.

    • Impact:

    • Highlights the high prevalence of depression in MS patients.
    • Identifies chronic fatigue and social status as key associated factors.
    • Informs clinical practice regarding the assessment and management of depression in MS.