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Updated: Aug 23, 2026
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
Primary choriocarcinoma of the lung
Yoshiki Umemori1, Akio Hiraki, Keisuke Aoe
1Department of Respiratory Surgery, National Sanyo Hospital, Respiratory Disease Center, Yamaguchi, Japan. umemori@sanyou-dr.jp
Abstract:
Primary choriocarcinoma (PCC) of the lung is extremely rare, with about 25 cases previously reported. We describe here a patient with PCC of the lung and review previously described cases to establish the clinical characteristics and most appropriate management of this disease. Survival for patients treated with both surgery and chemotherapy was longer than for patients treated with surgery alone, chemotherapy alone, or optional supportive care. Multivariate analysis of prognostic factors revealed that treatment with both surgery and chemotherapy had independent prognostic significance. Our analysis including previous cases suggests that resection followed by adjuvant chemotherapy is the most effective treatment.
