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[Acromegaly and sleep apnea].

J J Blanco Pérez1, M A Blanco-Ramos, C Zamarrón Sanz

  • 1Servicio de Neumología, Complexo Hospitalario Ourense, Ourense, Spain. xosej@tiscali.es

Archivos De Bronconeumologia
|July 28, 2004
PubMed
Summary

Acromegaly patients frequently experience sleep apnea-hypopnea syndrome (SAHS), with over half showing sleep apneas. SAHS prevalence was 29.4% and not linked to hormonal activity or cephalometric differences.

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Area of Science:

  • Endocrinology
  • Sleep Medicine
  • Pulmonology

Context:

  • Acromegaly, a condition caused by excess growth hormone, is linked to various comorbidities.
  • Sleep apnea-hypopnea syndrome (SAHS) is a known complication of acromegaly.
  • Understanding SAHS prevalence and characteristics in acromegaly is crucial for patient management.

Purpose:

  • To determine the prevalence of SAHS in acromegaly patients.
  • To characterize acromegalic patients with and without SAHS.
  • To explore correlations between SAHS, hormonal activity, and cephalometric features.

Summary:

  • This study assessed 17 acromegaly patients using polysomnography and hormonal level measurements.
  • A high prevalence of sleep apneas (58.8%) and SAHS (29.4%) was observed.

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  • No significant correlation was found between SAHS, growth hormone/IGF-1 levels, or cephalometric variables.

    • Impact:

    • The findings highlight a significant burden of sleep-disordered breathing in acromegaly.
    • Early identification and management of SAHS in acromegaly patients may improve outcomes.
    • This research contributes to a better understanding of acromegaly's multifaceted impact on health.