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Updated: Aug 23, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Non-melanotic skin tumors of the upper extremity
Sarvam P TerKonda1, Galen Perdikis
1Department of Plastic Surgery, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224, USA. terkonda.sarvam@mayo.edu
Abstract:
Most non-melanotic skin cancers involving the upper extremities are squamous cell and basal cell carcinomas. Ultraviolet sun light, fair complexion, and advancing age are important risk factors. Because of their high prevalence, the hand surgeon must be familiar with the diagnosis and clinical management of non-melanotic skin tumors. Early detection ultimately decreases the morbidity associated with the locally destructive nature of these tumors. Following diagnosis, the appropriate steps for management include wide surgical excision with pathologic conformation of normal margins and lymph node dissection for clinically positive nodes
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