Related Experiment Video

Updated: Aug 23, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Endocrine disorders in the neonate

Paola A Palma Sisto1

  • 1Department of Pediatrics, Section of Pediatric Endocrinology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. ppalma@mail.mcw.edu

Pediatric Clinics of North America
|July 28, 2004
PubMed

Insights

Recent advances in genetic data have improved the diagnosis and management of newborn endocrine disorders. This review covers key endocrine conditions presenting in infants.

Area of Science:

  • Pediatric Endocrinology
  • Neonatology
  • Medical Genetics

Background:

  • Endocrine disorders in newborns require specialized diagnostic and management approaches.
  • Recent years have seen significant advancements in understanding the genetic basis of these conditions.
  • Genetic data has expanded the scope of diagnostic evaluation and treatment strategies for affected infants.

Purpose of the Study:

  • To provide a general overview of endocrine disorders in the newborn population.
  • To highlight the impact of recent genetic discoveries on neonatal endocrinology.
  • To synthesize current knowledge on the presentation, diagnosis, and management of endocrine diseases in neonates.

Main Methods:

  • Literature review of recent studies on neonatal endocrine disorders.
  • Synthesis of information regarding genetic etiologies and their clinical implications.
  • Overview of diagnostic tools and therapeutic interventions.

Main Results:

  • Genetic data has revolutionized the understanding and diagnosis of congenital endocrine diseases.
  • New insights into molecular pathways have led to more targeted management strategies.
  • The article reviews common and rare endocrine conditions encountered in newborns.

Conclusions:

  • A comprehensive understanding of genetic factors is crucial for diagnosing and managing neonatal endocrine disorders.
  • Early and accurate diagnosis significantly impacts infant outcomes.
  • Continued research in molecular genetics will further refine clinical practice in pediatric endocrinology.

More Related Videos

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Related Concept Videos

Adrenal Gland Disorders01:27

Adrenal Gland Disorders

Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and lactation.
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Structures of the Endocrine System00:59

Structures of the Endocrine System

The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral stimuli,...