Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Decreased lung capillary blood volume post-exercise is compensated by increased membrane diffusing capacity.

D P Johns1, D Berry, M Maskrey

  • 1Discipline of Medicine, School of Medicine, University of Tasmania, 7001 Hobart, Tasmania, Australia.

European Journal of Applied Physiology
|July 28, 2004
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Light Pseudoscalar Bosons, Pair-Produced in Higgs Boson Decays in the Four-Electron Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

First Evidence for Mixing-Induced CP Violation in B_{s}^{0}→J/ψϕ(1020) Decays in pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

Observation of Suppressed Charged-Particle Production in Ultrarelativistic Oxygen-Oxygen Collisions.

Physical review letters·2026
Same author

Measurement of D^{0} Meson Photoproduction in Ultraperipheral Heavy Ion Collisions.

Physical review letters·2026
Same author

Observation of tWZ Production at the CMS Experiment.

Physical review letters·2026
Same author

First Exclusive Reconstruction of the B^{*+}, B^{*0}, and B_{s}^{*0} Mesons and Precise Measurement of Their Masses.

Physical review letters·2026

Intense exercise temporarily reduces lung diffusing capacity for carbon monoxide (DLCO) by decreasing pulmonary capillary blood volume (Vc), not due to edema. This suggests blood redistribution away from the lungs post-exercise.

Area of Science:

  • Physiology
  • Pulmonary Function Testing
  • Exercise Science

Background:

  • The diffusing capacity of the lung for carbon monoxide (DLCO) decreases post-intense exercise.
  • Proposed mechanisms include pulmonary edema or reduced pulmonary capillary blood volume (Vc).

Purpose of the Study:

  • To investigate the mechanisms behind post-exercise DLCO reduction.
  • To measure DLCO, Vc, and membrane diffusing capacity (Dm) following maximal exercise.

Main Methods:

  • Nine healthy females underwent maximal treadmill exercise.
  • DLCO, Vc, and Dm were measured using a rebreathing method before and up to 24 hours post-exercise.

Main Results:

  • DLCO decreased for 3 hours post-exercise, returning to baseline by 16 hours.

Related Experiment Videos

  • Pulmonary capillary blood volume (Vc) significantly decreased by 21.2% at 3 hours.
  • Membrane diffusing capacity (Dm) increased by 14.7% at 3 hours.

    • Conclusions:

    • The increase in Dm suggests the DLCO fall is not due to edema or blood-gas barrier injury.
    • Reduced DLCO is consistent with blood redistribution away from the lungs.
    • Reciprocal changes in Dm and Vc indicate improved gas transfer despite reduced Vc, possibly due to red blood cell reorientation.