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Updated: Aug 23, 2026

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in febrile seizures
I-Ching Chou1, Chang-Hai Tsai, Cheng-Chun Lee
1Departments of Pediatrics, China Medical University Hospital, Taichung, Taiwan.
Abstract:
Various studies have shown that brain-derived neurotrophic factor (BDNF) increased neuronal excitability. We tested that BDNF might be involved in the etiology of febrile seizures (FSs). A total of 186 Taiwanese children were divided into two groups: (1) FSs (n = 104); (2) normal control subjects (n = 83). A single base pair polymorphism SNP6265 (Val66Met) at position 196 was analyzed. Our findings suggest that the BDNF polymorphisms were not candidate genetic markers.
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