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Updated: Aug 23, 2026

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

Genome-wide patterns of nucleotide substitution reveal stringent functional constraints on the protein sequences of

Robert Friedman1, John W Drake, Austin L Hughes

  • 1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina 29208, USA.

Genetics
|July 29, 2004
PubMed

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