Related Experiment Video
Updated: Aug 4, 2026
08:08
Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
Published on: June 18, 2013
Best practice no 178. Examination of the human placenta
B Hargitai1, T Marton, P M Cox
1No 1 Department of Obstetrics and Gynecology, Semmelweis University Budapest, Baross u. 27, 1088 Budapest, Hungary.
Journal of Clinical Pathology
|July 29, 2004
Summary
Standardizing placental examination is crucial due to its underexplored nature and inconsistent diagnostic methods. This ensures optimal benefit from histopathology reports for maternal and fetal health.
Area of Science:
- Obstetrics and Gynecology
- Pathology
- Perinatal Medicine
Background:
- The human placenta remains an understudied organ with no established gold standards for clinical examination.
- Histological reporting of placental findings is inconsistent, variable in quality, and suffers from significant interobserver variability.
Framework:
- This article reviews current clinical indications for placental examination and recognized clinicopathological correlations.
- It highlights the need for standardized placental examination methods to maximize diagnostic utility.
Implementation:
- Histopathological examination of the placenta can reveal critical information regarding maternal and fetal health.
- This diagnostic approach aids in identifying treatable maternal conditions and recurrent or inherited placental/fetal disorders.
Implications:
- Standardization of placental examination protocols is essential for improving diagnostic accuracy and clinical utility.
- Improved placental diagnostics can lead to better management of pregnancy complications and informed reproductive planning.
