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Mondini dysplasia and pyogenic meningitis

Milind S Tullu1, Shilpa S Khanna, Jaishree R Kamat

  • 1Department of Pediatrics, Seth G. S. Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, India. milindtullu@yahoo.com

Indian Journal of Pediatrics
|July 29, 2004
PubMed

Insights

Mondini dysplasia, a rare inner ear malformation, can cause recurrent meningitis in children. Early diagnosis and surgical repair are crucial for managing this condition, especially with associated hearing loss.

Area of Science:

  • Otolaryngology
  • Pediatric Neurology
  • Neurosurgery

Background:

  • Recurrent pyogenic meningitis in children poses significant health challenges.
  • Mondini dysplasia is an uncommon congenital inner ear anomaly.
  • Cerebrospinal fluid (CSF) leaks can lead to meningitis.

Observation:

  • A case of an 11-year-old girl with recurrent meningitis and sensorineural deafness is presented.
  • High-resolution computed tomography (HRCT) and MRI confirmed Mondini dysplasia with a CSF-perilymph fistula.
  • The patient experienced a fifth episode of meningitis before diagnosis.

Findings:

  • Mondini dysplasia associated with a CSF-perilymph fistula was identified as the cause of recurrent meningitis.
  • Surgical intervention to close the defect was successfully performed.
  • The diagnosis was supported by imaging studies of the temporal bone and brain.

Implications:

  • Mondini dysplasia should be considered in the differential diagnosis of recurrent meningitis in pediatric patients.
  • Sensorineural deafness may be an indicator of underlying inner ear anomalies causing meningitis.
  • Prompt diagnosis and surgical management can prevent further meningitis episodes and complications.

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