[In vitro activity of various antibiotic agents against gram-negative nosocomial bacteremia pathogens]

Empiric therapy is essential in Gram-negative nosocomial bacteremia. Therapy is initiated according to the most frequently isolated organisms and their susceptibility profiles. In order to determine the appropriate antibiotics for this purpose, a study was conducted in 176 blood isolates in Hacettepe University Hospitals. Antibiotic susceptibilities were determined by microbroth dilution tests. The results showed amikacin, ofloxacin and ciprofloxacin to be the most effective antibiotics in-vitro. It is suggested that these agents should be employed in empirical therapy until the causative agent is defined.