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Published on: June 4, 2017
Development and validation of school-based asthma and allergy screening questionnaires in a 4-city study
Susan Redline1, Rebecca S Gruchalla, Raoul L Wolf
1Department of Pediatrics. Case Western Reserve University and Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA.
Insights
School-based questionnaires effectively screen for undiagnosed asthma and allergies in children. A student questionnaire (SQ) showed high sensitivity for detecting these common childhood conditions.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Public Health Screening
Background:
- Asthma and allergies are frequently undiagnosed in pediatric populations.
- Schools offer a unique setting for widespread screening of nearly all children.
- Early identification is crucial for managing childhood respiratory conditions.
Purpose of the Study:
- To assess the feasibility and validity of questionnaire-based tools for identifying undiagnosed asthma and respiratory allergies in school-aged children.
- To evaluate the effectiveness of student questionnaires (SQ) and parent questionnaires (PQ) in diverse community settings.
Main Methods:
- Development and administration of a student questionnaire (SQ) and a parent questionnaire (PQ) in four diverse communities.
- Validation of questionnaire responses against standardized clinical assessments in children aged 7-13.
- Evaluation of sensitivity, specificity, and predictive values of questionnaire items using expert consensus.
Main Results:
- Individual questionnaire items showed modest to moderate predictive value for asthma and allergies (ORs 2.5-5.0).
- A 7-item SQ asthma screen achieved 80% sensitivity and 70% specificity for asthma detection (OR 9.3).
- A 2-item SQ allergy screen demonstrated 81% sensitivity and 42% specificity for allergy detection.
Conclusions:
- A 9-item student questionnaire (SQ) or a 10-item parent questionnaire (PQ) are viable tools for screening asthma and allergies in various settings.
- The student questionnaire (SQ) offers a sensitive method for identifying children with previously undiagnosed asthma and allergies.
Background:
Asthma and allergies are commonly undiagnosed in children. Schools provide settings for potentially accessing almost all children for asthma and allergy screening.
Objective:
To evaluate the feasibility and validity of using a questionnaire-based screening tool to identify undiagnosed asthma and respiratory allergies in children in kindergarten to grade 6.
Methods:
A student questionnaire (SQ) and a parent questionnaire (PQ) were developed, administered in 4 diverse communities, and validated against standardized clinical assessments. Children without diagnosed asthma and representing a range of symptoms participated in a validation study that consisted of independent, standardized, clinical assessments. Sensitivity, specificity, and predictive values for questionnaire items were evaluated against expert consensus designations.
Results:
A total of 190 children (age range, 7-13 years) completed the validation study. Affirmative responses to individual questions from either the SQ or PQ regarding asthma and allergy were modestly to moderately predictive of the clinical assessments (odds ratios, generally 2.5-5.0). When considering a positive asthma screen as affirmative responses to 3 of the best 7 SQ asthma questions, the odds ratio for asthma was 9.3 (95% confidence interval, 4.1-21.1), with 80% sensitivity and 70% specificity. Considering the allergy screen as positive based on affirmative response to either of the 2 SQ allergy questions yielded 81% sensitivity and 42% specificity.
Conclusions:
Either a 9-item SQ or a 10-item PQ can be used in diverse settings to screen for asthma and respiratory allergies. The SQ, obtained by directly screening students, may provide a sensitive approach for detecting children with previously undiagnosed asthma and allergies.
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