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Updated: Oct 9, 2026

15:53
Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells
Published on: August 21, 2013
On the origins of mitosis and why it is involved in cancer
1Department of Pathology, University of Sheffield Medical School, UK.
Medical Hypotheses
|June 1, 1992
Abstract:
It is suggested that mitosis arose in evolution as a mechanism for 'excreting' damaged DNA (mutations). The mechanism for excretion involved replication of the DNA and was thus a pre-adaptation that could be used for cell replication. In multicellular organisms the mutated cells cannot always be lost and may persist as neoplasms.
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