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Leukemias and multiple myeloma.

Vincenzo De Lisi1

  • 1Divisione di oncologia, Dipartimento 21 medicina, Azienda ospedaliera, via Gramsci 14, 43100 Parma.

Epidemiologia E Prevenzione
|July 30, 2004
PubMed
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Adult leukemia incidence remained stable from 1986-1997, with decreasing mortality. Multiple myeloma incidence sharply increased, while its mortality remained stable, based on Italian cancer registry data.

Area of Science:

  • Oncology
  • Epidemiology
  • Public Health

Background:

  • Leukemia and multiple myeloma are significant hematologic malignancies.
  • Understanding temporal trends in cancer incidence and mortality is crucial for public health planning.

Purpose of the Study:

  • To analyze temporal trends in adult leukemia and multiple myeloma incidence and mortality in Italy.
  • To identify significant changes in these hematologic malignancies over a defined period.

Main Methods:

  • Utilized data from the Italian Network of Cancer Registries (pool AIRT) database.
  • Analyzed temporal trends for leukemia (15+ years) and multiple myeloma cases and deaths between 1986 and 1997.

Main Results:

  • Leukemia incidence rates were stable (10,946 cases), but mortality decreased by 1-2% annually, notably in males (8,265 deaths).

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  • Multiple myeloma incidence rates significantly increased by approximately 3% per year (6,535 cases), while mortality remained stable (4,310 deaths).

    • Conclusions:

    • Adult leukemia shows a favorable mortality trend despite stable incidence.
    • The rising incidence of multiple myeloma warrants further investigation into potential contributing factors.