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Updated: Aug 23, 2026

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
Published on: June 13, 2025
[General introduction to clinical chronobiology and the therapeutic manipulation of biological rhythms]
Pere A Martínez-Carpio1, August Corominas
1Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Barcelona, Barcelona, Spain.
Abstract:
In humans, most clinical variables follow biological rhythms approaching to a mathematical function defined by the cosmic-climatic rhythm. Chronophysiology, chronopathology, chronopharmacology, chronotherapy and phototherapy have common elements frequently studied in a disperse manner, thus making it difficult a global understanding of clinical chronobiology as a unitary and well-characterized discipline. This review focuses on medical chronobiology, which is much more technical since it only gathers those directives of clinical chronobiology having a health-care impact on daily practice.
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