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Scintigraphic evaluation of cardiac metabolism in multicentric Castleman's disease

Shinro Matsuo1, Yasuyuki Nakamura, Ichiro Nakae

  • 1Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu.

Internal Medicine (Tokyo, Japan)
|July 31, 2004
PubMed

Insights

Multicentric Castleman

Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Oncology

Background:

  • Heart failure can present insidiously.
  • Multicentric Castleman's disease is a rare lymphoproliferative disorder.

Observation:

  • A 72-year-old woman presented with heart failure.
  • She was diagnosed with multicentric Castleman's disease.

Findings:

  • Myocardial perfusion imaging with technetium-99m tetrofosmin showed normal left ventricular uptake.
  • 123I-BMIPP imaging revealed reduced uptake in the apical myocardium, indicating metabolic abnormalities.

Implications:

  • This case highlights the utility of dual-tracer myocardial imaging in evaluating heart failure.
  • Nuclear imaging can detect metabolic changes in the myocardium associated with Castleman's disease.

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