Related Experiment Video
Updated: Aug 23, 2026

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Antifungal susceptibility of 50 Candida isolates from invasive mycoses in Chile
Victor Silva1, Daniel Alvarado, Maria Christina Diaz
1Microbiology and Mycology Program, Biomedical Sciences Institute, School of Medicine, University of Chile, Santiago, Chile. vsilva@med.uchile.cl
Abstract:
We determined the antifungal susceptibility of 50 Candida isolates from invasive mycoses in intensive care unit patients in Chile. Candida albicans (27 isolates) and C. parapsilosis (12 isolates) were the most common etiologic species. Candida glabrata (five isolates) was isolated only from children. Our data are consistent with those of recent Brazilian and Argentinean studies but differ from those of some US, Canadian and Norwegian studies, in which the relatively azole-resistant C. glabrata was the predominant non-C. albicans species seen. All isolates in this study were susceptible to amphotericin B. Itraconazole and fluconazole resistance were observed in 6 and 4% of the isolates, respectively.
Related Concept Videos
Candidiasis
Antifungal Agents
Cryptococcal Meningitis

