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The genetics of hypogammaglobulinemia
Bodo Grimbacher1, Alejandro A Schäffer, Hans-Hartmut Peter
1Division of Rheumatology and Clinical Immunology, Medical School, University of Freiburg, Germany. grimbacher@medizin.ukl.uni-freiburg.de
Abstract:
Etiologies for human hypogammaglobulinemias are diverse and include genetic and nongenetic causes. Although recent reviews focus on the complex genetics of common variable immunodeficiency, in this review, we survey different causes of hypogammaglobulinemias and discuss possible mechanisms.
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