Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Population screening for lung cancer.

Peter Armstrong1, Janet E Husband, John A Holemans

  • 1St Bartholomew's Hospital, London.

Hospital Medicine (London, England : 1998)
|August 4, 2004
PubMed
Summary

Low-dose chest computed tomography can find early lung cancers in asymptomatic individuals. However, evidence is needed to confirm if widespread screening programs offer more benefits than harms cost-effectively.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis.

The Lancet regional health. Europe·2021
Same author

Use of parecoxib by continuous subcutaneous infusion for cancer pain in a hospice population.

BMJ supportive & palliative care·2017
Same author

The impact of trained radiographers as concurrent readers on performance and reading time of experienced radiologists in the UK Lung Cancer Screening (UKLS) trial.

European radiology·2017
Same author

Comparing the performance of trained radiographers against experienced radiologists in the UK lung cancer screening (UKLS) trial.

The British journal of radiology·2016
Same author

The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer.

Health technology assessment (Winchester, England)·2016
Same author

Investigation of Nanoscale Interactions by Means of Subharmonic Excitation.

The journal of physical chemistry letters·2015

Area of Science:

  • Oncology
  • Radiology
  • Public Health

Background:

  • Multiple studies confirm the feasibility of diagnosing early-stage lung cancers using low-dose chest computed tomography (LDCT).
  • LDCT is effective in detecting small, stage 1 lung cancers in asymptomatic individuals at high risk.
  • The clinical utility of LDCT screening programs remains under investigation.

Purpose of the Study:

  • To evaluate the overall benefit-risk balance of implementing a chest computed tomography screening program.
  • To determine if widespread LDCT screening for lung cancer is cost-effective.
  • To assess the net health outcome of introducing LDCT screening in at-risk populations.

Main Methods:

  • Review of existing studies on LDCT for lung cancer diagnosis.
  • Analysis of diagnostic accuracy for early-stage lung cancers.
  • Health economic evaluation of screening program implementation.

Main Results:

  • The feasibility of diagnosing small stage 1 lung cancers with LDCT is established.
  • Data on the net benefit (good vs. harm) of a screening program is currently insufficient.
  • Cost-effectiveness analysis for LDCT screening programs requires further investigation.

Conclusions:

  • While LDCT is feasible for early lung cancer detection, its net benefit in screening programs needs further proof.
  • The cost-effectiveness of widespread LDCT screening remains an open question.
  • More research is required to establish the value of LDCT screening programs in clinical practice.

Related Experiment Videos