Related Experiment Video
Updated: Aug 23, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
Computer-assisted diagnosis by temporal subtraction in postoperative brain tumor patients: a feasibility study
Eero Ilkko1, Kari Suomi, Ari Karttunen
1Department of Diagnostic Radiology, Oulu University Hospital, PL 50, 90029 OYS, Finland. eero.ilkko@ppshp.fi
Rationale And Objectives:
To introduce and evaluate a novel, image fusion-based technique that can be used to compare the findings of primary and control brain magnetic resonance imaging scans, with special attention to the differences found in this comparison.
Materials And Methods:
A new technique named "colored difference mapping" was applied to the brain examinations of five patients. The possible changes in the magnetic resonance imaging findings were analyzed by the colored difference mapping technique and by using conventional film reading and the results were compared.
Results:
Colored difference mapping accurately depicts the differences between successive magnetic resonance images and reveals small changes that are difficult to perceive in a visual evaluation.
Conclusion:
Colored difference mapping is suitable for comparison of images between two different radiologic examinations and helps to show even minimal changes in brain tissues.
