[Assessment of tuberculosis recurrence risk in phenotyping haptoglobin in patients with post-tuberculous residual changes in the lungs]

Haptoglobin (Hp) phenotyping was carried out in 223 healthy subjects of Moscow and 504 subjects from the inactive groups of a dispensary record who were earlier taken off the record due to recovery. It was found that the occurrence frequency of various Hp types among the healthy population of Moscow corresponds to that of the European region of this country. In groups of subjects with post-tuberculous residual changes accumulation of carriers of homozygous Hp 2:2 occurs at the expense of reduction of Hp 2:2 occurrence frequency. Recurrences of the disease in subjects with post-tuberculous residual changes took place significantly more often in both homozygous Hp variants carriage and had a graver course, which should be taken into consideration in formation of the most threatening high-risk groups of pulmonary tuberculosis recurrences that require special attention and preventive measures.