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Published on: December 11, 2017
Late survival after elective repair of aortic aneurysms detected by screening
J C Taylor1, E Shaw, M R Whyman
1Gloucestershire Vascular Group, Gloucestershire Royal Hospital, Great Western Road, Gloucester GL1 3NN, UK.
Insights
Men undergoing elective repair of abdominal aortic aneurysms (AAA) detected via screening had better survival rates than those with incidentally detected AAA. This survival advantage is linked to younger age at surgery for screen-detected cases.
Area of Science:
- Vascular Surgery
- Public Health Screening
- Epidemiology
Background:
- Abdominal aortic aneurysm (AAA) repair outcomes are critical for patient survival.
- Screening programs aim to detect AAA earlier for potential improved outcomes.
- Comparing outcomes of screen-detected versus incidentally-detected AAA is essential.
Purpose of the Study:
- To determine if elective repair of screen-detected AAA offers a survival benefit compared to incidentally detected AAA.
- To analyze survival rates and mortality following AAA repair based on detection method.
Main Methods:
- Retrospective analysis of 424 men undergoing elective AAA repair (1990-1998).
- Comparison of survival data between screen-detected (n=181) and incidentally-detected (n=243) AAA groups.
- Survival curves analyzed using regression and log-rank testing with minimum 5-year follow-up.
Main Results:
- Lower 30-day postoperative mortality for screen-detected AAA (4.4%) versus incidental (9.0%).
- Significantly better 5-year (78% vs. 65%) and 10-year (63% vs. 40%) survival rates for screen-detected AAA.
- Multivariate analysis indicated younger age at surgery for screen-detected AAA was a key factor.
Conclusions:
- Elective AAA repair following ultrasound screening is associated with improved long-term survival.
- Patients with screen-detected AAA were younger at the time of surgical repair, contributing to better outcomes.
- Screening for abdominal aortic aneurysms may lead to more favorable surgical outcomes.
Background:
The aim of this study was to examine whether there was any survival advantage in men following elective repair of an abdominal aortic aneurysm (AAA) detected by ultrasound screening compared to those with an AAA detected incidentally.
Methods:
A total of 424 men underwent elective AAA repair between 1990 and 1998; 181 were detected in an aneurysm screening programme and 243 were diagnosed incidentally. Follow-up survival data were collected until 2003 (minimum 5 years) and survival curves were compared using regression analysis.
Results:
The postoperative 30-day mortality rate was significantly lower in men whose aneurysms were detected by screening (4.4%), compared with those detected incidentally (9.0%). Similarly, 5-year survival (78% vs. 65%) and 10-year survival rates (63% vs. 40%) were better after repair of a screen-detected AAA (p<0.0003 at all time intervals, by log rank testing). Multivariate analysis showed that this was largely due to the older age of men who had repair of an incidental AAA (71.2 vs. 67.1 years).
Conclusion:
Men who had elective repair of an AAA detected by screening had a better late survival rate than men whose aneurysm was discovered incidentally because they were younger at the time of surgery.
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